INSMNasdaqSEC EDGAREDGAR

INSMED Inc

Pharmaceutical Preparations·BRIDGEWATER, NJ·FY end 12/31·CIK 1104506

Board of Directors

9 members · 8 independent · FY 2023
DirectorRoleTenureAgeCommitteesIndep.Annual fees
William H. LewisCEO and Director12y55
David R. BrennanLead Independent Director10y70Comp$345,000
Alfred F. AltomariDirector12y65CompAudit$320,000
Elizabeth McKee AndersonDirector6y66NCG$310,000
David W.J. McGirrDirector11y69Audit$320,000
Clarissa DesjardinsDirector5y57Tech
Carol A. SchaferDirector4y60AuditNCG$315,000
Leo LeeDirector6y54CompTech$317,500
Melvin SharokyDirector23y73NCGTech

Risk-factor diff

FY 2025 10-K vs. FY 2024
+211 new199 removed

Net-new paragraphs in the most recent 10-K's Item 1A. Companies rarely add risk language without a real reason — additions here are often a leading signal of management concerns.

NEW · FY 2025

Our prospects are highly dependent on the success of our approved products, ARIKAYCE and BRINSUPRI. If we are unable to successfully market, commercialize and maintain approval for ARIKAYCE and BRINSUPRI, our business, financial condition, results of operations and prospects and the value of our common stock may be materially adversely affected.

NEW · FY 2025

We may not be able to obtain regulatory approval for ARIKAYCE in front-line NTM lung disease, for ARIKAYCE or BRINSUPRI in additional markets or for our product candidates. Any such failure to obtain regulatory approvals may materially adversely affect us.

NEW · FY 2025

The commercial success of ARIKAYCE and BRINSUPRI depend on market acceptance by physicians, patients, third-party payors and others in the healthcare community, and the commercial success of our product candidates, if approved, will similarly depend on market acceptance.

NEW · FY 2025

We are subject to substantial, ongoing regulatory requirements, including with respect to advertising and promotion, and failure to comply with these requirements may lead to enforcement action or otherwise materially harm our business.

NEW · FY 2025

If we are unable to obtain or maintain adequate reimbursement from government or third-party payors for ARIKAYCE, BRINSUPRI or our product candidates, if approved, or if we are unable to obtain or maintain acceptable prices for ARIKAYCE, BRINSUPRI, or, if approved, our product candidates, our prospects for generating revenue and achieving profitability may be materially adversely affected.

+ 25 more new paragraphs not shown

Policies & disclosures

Clawback, anti-hedging, stock ownership, and related-party policies will populate from extracted proxy sections.